Ticlopidine Hydrochloride

From ConceptWiki

•  Definition

  Text	Reference information	Community	NLM
  The hydrochloride salt form of ticlopidine, a thienopyridine derivative with anticoagulant property. Ticlopidine hydrochloride irreversibly inhibits adenosine-diphosphate (ADP)-induced platelet-fibrinogen binding by binding to the glycoprotein (GP) IIb/IIIA complex, one of the two purinergic receptors activated by ADP. Inhibition of the receptor activation causes the inhibition of adenylyl cyclase, results in decreased levels of cyclic adenosine monophosphate and thereby interferes with platelet membrane function and subsequent, platelet-platelet interaction, release of platelet granule constituents and prolongation of bleeding time.	Reference information Connection Element Community NLM source National Cancer Institute Thesaurus, 2007-05E

•  Also known as

  Term	Preferred in	Reference information	Community	NLM
  Ticlopidine Hydrochloride	life sciences	Reference information Connection Element Identifier Community NLM source USP Model Guidelines, 2004 MTHU000889 source National Cancer Institute Thesaurus, 2007-05E C47756 source Multum MediSource Lexicon, 2008-01-01 31069 source RxNorm Vocabulary, 07AC-080131F 97 source Medical Subject Headings, 2005-2005-01-17 D013988
  ticlopidine hydrochloride	life sciences	Reference information Connection Element Identifier Community NLM source Multum MediSource Lexicon, 2008-01-01 5582
  TICLOPIDINE HYDROCHLORIDE	life sciences	Reference information Connection Element Identifier Community NLM source Veterans Health Administration National Drug File, 2007-12-18 4020458 source National Drug File - Reference Terminology, 2004-01 C20814 source National Cancer Institute Thesaurus, 2007-05E C47756 source Metathesaurus FDA National Drug Code Directory, 2008-01-04 48423
  Ticlopidine hydrochloride	life sciences	Reference information Connection Element Identifier Community NLM source Metathesaurus FDA Structured Product Labels, 2008-01-23 A1L4914FMF source SNOMED Clinical Terms, 2008-01-31 Identifier » Element Community NLM 395904008 412521005
  Hydrochloride, Ticlopidine	life sciences	Reference information Connection Element Identifier Community NLM source Medical Subject Headings, 2005-2005-01-17 D013988
  Ticlopidine hydrochloride (substance)		Reference information Connection Element Identifier Community NLM source SNOMED Clinical Terms, 2008-01-31 395904008
  TICLOPIDINE HYDROCHLORIDE PREPARATION		Reference information Connection Element Identifier Community NLM source National Drug File - Reference Terminology, 2004-01 C20812
  Ticlopidine hydrochloride (product)		Reference information Connection Element Identifier Community NLM source SNOMED Clinical Terms, 2008-01-31 412521005
  Thieno(3,2-c)pyridine, 5-((2-chlorophenyl)methyl)-4,5,6,7-tetrahydro-, Hydrochloride		Reference information Connection Element Identifier Community NLM source National Cancer Institute Thesaurus, 2007-05E C47756
  5-(o-Chlorobenzyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridinium Chloride		Reference information Connection Element Identifier Community NLM source National Cancer Institute Thesaurus, 2007-05E C47756
  Panaldine		Reference information Connection Element Identifier Community NLM source National Cancer Institute Thesaurus, 2007-05E C47756

•  Functional information

  Connection	Element	Reference information	Community	NLM
  has physiologic effect	Decreased Platelet Aggregation	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  may prevent	Ischemia	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  may prevent	Thromboembolism	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  may prevent	Venous Thrombosis	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  may treat	Intracranial Embolism and Thrombosis	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01

•  Structural and physical information

  Connection	Element	Reference information	Community	NLM
  has ingredient	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01

•  Reference information

  Connection	Element	Identifier	Community	NLM
  source	UMLS	C0000598
  source	SNOMED Clinical Terms, 2008-01-31	Identifier » Element Community NLM 395904008 412521005
  source	Metathesaurus FDA Structured Product Labels, 2008-01-23	A1L4914FMF
  source	Veterans Health Administration National Drug File, 2007-12-18	4020458
  source	RxNorm Vocabulary, 07AC-080131F	97
  source	Metathesaurus FDA National Drug Code Directory, 2008-01-04	48423
  source	Multum MediSource Lexicon, 2008-01-01	Identifier » Element Community NLM 31069 5582
  source	SNOMED Terminos Clinicos (SNOMED CT), Edicion en Espanol, Distribucion Internacional, Octubre de 2007, 2007-10-31	Identifier » Element Community NLM 395904008 412521005
  source	National Cancer Institute Thesaurus, 2007-05E	C47756
  source	USP Model Guidelines, 2004	MTHU000889
  source	National Drug File - Reference Terminology, 2004-01	Identifier » Element Community NLM C20814 C20812
  source	Medical Subject Headings, 2005-2005-01-17	D013988

•  Tags

  Tag	Reference information	Community	NLM
  Ticlopidine	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01 source SNOMED Terminos Clinicos (SNOMED CT), Edicion en Espanol, Distribucion Internacional, Octubre de 2007, 2007-10-31 source SNOMED Clinical Terms, 2008-01-31
  Antiplatelet Agents	Reference information Connection Element Community NLM source National Cancer Institute Thesaurus, 2007-05E
  organic chemical
  pharmacologic substance

•  Pointers to Ticlopidine Hydrochloride

  Other concept	Connection	Concept	Reference information	Community	NLM
  Ticlopidine	has a broader relationship	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source USP Model Guidelines, 2004 source National Drug File - Reference Terminology, 2004-01 source SNOMED Terminos Clinicos (SNOMED CT), Edicion en Espanol, Distribucion Internacional, Octubre de 2007, 2007-10-31 source RxNorm Vocabulary, 07AC-080131F source Medical Subject Headings, 2005-2005-01-17
  Antiplatelet Agents	has a broader relationship	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Cancer Institute Thesaurus, 2007-05E
  Ticlopidine Hydrochloride	has relationship other than synonymous, narrower, or broader	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source SNOMED Clinical Terms, 2008-01-31 source SNOMED Terminos Clinicos (SNOMED CT), Edicion en Espanol, Distribucion Internacional, Octubre de 2007, 2007-10-31
  Blood Coagulation Disorders	has relationship other than synonymous, narrower, or broader	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  Intracranial Embolism and Thrombosis	has relationship other than synonymous, narrower, or broader	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  Drug Allergy	has relationship other than synonymous, narrower, or broader	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  Hemorrhage	has relationship other than synonymous, narrower, or broader	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  Ischemia	has relationship other than synonymous, narrower, or broader	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  Liver diseases	has relationship other than synonymous, narrower, or broader	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  Thromboembolism	has relationship other than synonymous, narrower, or broader	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  Ticlopidine	has relationship other than synonymous, narrower, or broader	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Cancer Institute Thesaurus, 2007-05E
  Venous Thrombosis	has relationship other than synonymous, narrower, or broader	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  Ticlopidine 250 MG Oral Tablet [Ticlid]	has relationship other than synonymous, narrower, or broader	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source Metathesaurus FDA Structured Product Labels, 2008-01-23 source Multum MediSource Lexicon, 2008-01-01
  Ticlodix	has relationship other than synonymous, narrower, or broader	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source UMLS Metathesaurus
  Decreased Platelet Aggregation	has relationship other than synonymous, narrower, or broader	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  Ticlopidine 250 MG Oral Tablet	has relationship other than synonymous, narrower, or broader	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source UMLS Metathesaurus source SNOMED Clinical Terms, 2008-01-31 source Metathesaurus FDA Structured Product Labels, 2008-01-23 source Veterans Health Administration National Drug File, 2007-12-18 source Multum MediSource Lexicon, 2008-01-01 source SNOMED Terminos Clinicos (SNOMED CT), Edicion en Espanol, Distribucion Internacional, Octubre de 2007, 2007-10-31 source National Drug File - Reference Terminology, 2004-01
  TICLOPIDINE HYDROCHLORIDE 250 MG	has relationship other than synonymous, narrower, or broader	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  FDA Established Names and Unique Ingredient Identifier Codes Terminology	has relationship other than synonymous, narrower, or broader	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Cancer Institute Thesaurus, 2007-05E
  Ticlopidine Hydrochloride	source asserted synonymy.	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source Medical Subject Headings, 2005-2005-01-17 source RxNorm Vocabulary, 07AC-080131F
  Ticlid	source asserted synonymy.	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Cancer Institute Thesaurus, 2007-05E
  Blood Coagulation Disorders	has contraindicated drug	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  Drug Allergy	has contraindicated drug	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  Hemorrhage	has contraindicated drug	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  Liver diseases	has contraindicated drug	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  Ticlopidine	has form	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source RxNorm Vocabulary, 07AC-080131F
  Ticlopidine Hydrochloride	has ingredient	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  Ticlopidine 250 MG Oral Tablet [Ticlid]	has ingredient	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source Metathesaurus FDA Structured Product Labels, 2008-01-23 source Multum MediSource Lexicon, 2008-01-01
  Ticlopidine 250 MG Oral Tablet	has ingredient	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source Metathesaurus FDA Structured Product Labels, 2008-01-23 source Veterans Health Administration National Drug File, 2007-12-18 source Multum MediSource Lexicon, 2008-01-01 source National Drug File - Reference Terminology, 2004-01
  TICLOPIDINE HYDROCHLORIDE 250 MG	has ingredient	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Drug File - Reference Terminology, 2004-01
  Ticlopidine Hydrochloride	has permuted term	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source Medical Subject Headings, 2005-2005-01-17
  Ticlid	has precise ingredient	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source RxNorm Vocabulary, 07AC-080131F
  Ticlopidine	has salt form	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Cancer Institute Thesaurus, 2007-05E
  FDA Established Names and Unique Ingredient Identifier Codes Terminology	subset includes concept	Ticlopidine Hydrochloride	Reference information Connection Element Community NLM source National Cancer Institute Thesaurus, 2007-05E
  Khaled Buresly	has interest	Ticlopidine Hydrochloride
  Lorenzo Dal Bo	has interest	Ticlopidine Hydrochloride
  Kiyomu Ishikawa	has interest	Ticlopidine Hydrochloride
  Shoko Kawaguchi	has interest	Ticlopidine Hydrochloride
  Antonio Marzo	has interest	Ticlopidine Hydrochloride
  Miyoko Mizushima	has interest	Ticlopidine Hydrochloride
  Masayuki Sakaki	has interest	Ticlopidine Hydrochloride

•  Information in other websites

  C0000598 in Concept Web